Best Way to Cure Nasal Polyps ( Nasal Polyps Research Study )

 


Researchers divided patients into eosinophilic Nasal Polyps and non-eosinophilic Nasal Polyps based on the infiltration of eosinophils in nasal polyp tissue. In non- eosinophilic patients, the reduction in nasal polyps was similar among the three groups. The results correlated with previous studies showing that high-dose budesonide nasal nebulization could significantly reduce the NP score in eosinophilic patients16,31 and the effect of high-dose local steroid treatment was greater than that of regular nasal spray treatment. According to the results of our study, oral steroids or high-dose local steroids might be unsuitable for non- eosinophilic patients, and might increase the risk of adverse events.

For eosinophilic Nasal Polyps patients, a regular dose of nasal spray might not be enough to con¬trol disease. Previous studies demonstrated that for patients with more than 27% tissue eosinophils, more than 50% of patients might suffer fromrecurrence in two years after surgery.  In our study, for eosinophilic Nasal Polyps patients, the reduction in Nasal Polyps  was significantly different in the nasal drop and oral steroid groups compared to that in the nasal spray group. 

After stratifying patients into different subgroups according to the eosinophil infiltration, patients with 30-50% tissue eosinophils showed a remarkably better response to high-dose local steroid treatment and patients with more than 50% tissue eosinophil showed a prominent response to oral steroid treatment. Therefore, high-dose local steroids and oral steroids could both improve the clinical outcome of eosinophilic patients. For patients with 30-50% tissue eosinophils, high-dose local ste¬roids might be recommended because of the comparable effect to that of oral steroids and lower rate of adverse effects. Meanwhile, for pa-tients with more than 50% tissue eosinophil infil¬tration and with a combination of diseases, such as diabetes and hypertension, which might not be suitable for oral steroids, high-dose local steroids might be an alternative choice. 

Read more :  How to Cure Nasal Polyps Naturally at Home ?

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