Nasal Polyps Researchs

Severe nasal polyposis can cause deformities of the nose and face. This phenomenon is called Woakes’ syndrome. The facial deformity in our patient was caused by pressure from nasal polyposis that filled the nasal cavity and paranasal sinuses. Using the midface degloving approach, we performed osteotomy of the nasal bone, shaved the .The facial deformity of Woakes’ syndrome involved the nasal and facial bones and nasal cartilaginous tissue. In severe cases, excessive prominence of the malar region and orbital hypertelorism have been reported . Patient had broadening of the nose and excessive prominence of the malar regions without orbital hypertelorism. We believe that inflammation associated with 30 years of chronic sinusitis caused enlargement of the nasal polyps, leading to the exertion of physical pressure on the neighbouring bones and cartilage.   Several reports discuss the cosmetic treatment of the nose after nasal polyp removal. Laff performed nasal plastic repair with osteo...

  Glucocorticoid is the first-line treatment for chronic rhinosinusitis with nasal polyps. However, the appropriate dose and the duration of treatment remain unknown. In China, nasal spray is widely used in Nasal Polyps patients, and patients with asthma or with recurrent nasal polyps will be treated with oral steroids for one to two weeks or even longer to control the symptoms.  However, an increasing number of studies have demonstrated that the regular dose of nasal spray is not enough for disease control. Although the safety of short- course oral steroids has been demonstrated by clinical trials, repeated use of short-course oral steroids for more than two courses per year may increase the risk of osteoporosis.Recently, some physicians have recommended high dose local steroids as an effective and safe way to treat Nasal Polyps. In clinical observation, the endoscopic score and clinical symptoms of recurrent Nasal Polyps patients improved significantly at the end of one to t...

  Researchers divided patients into eosinophilic Nasal Polyps and non-eosinophilic Nasal Polyps based on the infiltration of eosinophils in nasal polyp tissue. In non- eosinophilic patients, the reduction in nasal polyps was similar among the three groups. The results correlated with previous studies showing that high-dose budesonide nasal nebulization could significantly reduce the NP score in eosinophilic patients16,31 and the effect of high-dose local steroid treatment was greater than that of regular nasal spray treatment. According to the results of our study, oral steroids or high-dose local steroids might be unsuitable for non- eosinophilic patients, and might increase the risk of adverse events. For eosinophilic Nasal Polyps patients, a regular dose of nasal spray might not be enough to con¬trol disease. Previous studies demonstrated that for patients with more than 27% tissue eosinophils, more than 50% of patients might suffer fromrecurrence in two years after surgery....