What are Best Way to Treat Nose Polyps ?


Nose polyps ( chronicrhinosinusitis with nasal polyps ) is a heterogenous mucosalinflammation involving not only the paranasal sinuses but alsothe nose. An abnormal host response to infectious microorganisms,such as viruses and bacteria, has been suggested to be responsiblefor the persistent inflammation of the sinonasal mucosa.1Although data for the prevalence of viral infection in patientswith Nose polyps are conflicting, a high frequency of viral presence wasdemonstrated in nasal epithelial cells or lavage fluid of patientswith Nose polyps. 

It has been suggested that viral respiratory tractinfection  influences the development or progressive courseof Nose polyps through various means.5,6In vitrostudies demonstratedthat VRIs can damage the epithelial cells covering the sinonasalcavity, resulting in dysfunction of the epithelial barrier andincreased bacterial adhesion.

However, few studies have evaluatedwhether an apparent deficiency in antiviral immunity or the interferon response might represent a deficient innate immuneresponse in patients with Nose Polyps .The interferon response to VRIs occurs through patternrecognition receptors and Toll-like receptors. Glucocorticoids (oral or intranasal) and macrolide antibiotictreatment  are  recommended  for  patients  with Nose Polyps .Despitethe  known  beneficial  clinical  effects  of  glucocorticoids,glucocorticoid  treatment  is  also  known  to  enhance  viralreplication and is associated with prolonged viral isolation innasal washes during naturally occurring rhinovirus infection.Macrolides  exhibit  antimicrobial  activity  in  addition  toimmunomodulatory properties and inhibit the synthesis orsecretion of inflammatory cytokines. 

Read more :  How to Cure Nasal Polyps Permanently and Naturally at Home ?

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Is There Anyway to Cure Nasal Polyps without Surgery ?

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Chronic rhinosinusitis with nasal polyposis ( nose polyps ) is a numbrella term for a heterogeneous group of inflammatory disorders characterized by persistent polypoid inflammation ofthe sino nasal mucosa (>_12 weeks) and nasal obstruction. Symptoms are often severe and only partially responsive to treatment, and disease is commonly associated with difficult-to-treat asthma. There is an urgent unmet clinical need to understand the immuno pathology of Nasal polyps.  Several studies have indicated regional variation in nasal polyps endotypes. Western countries show a predominance of eosinophilic TH2-associated polyps, and Staphylococcus aureussuperantigens have beenimplicated in driving the TH2 response. Nasal polyps reveals frequent epithelial damage, a thickened  basementmembrane, oedema, fibrotic foci and a reduced number of vessels and glands. The stroma of Nasal polyps contains abundant infiltration of inflammatory cells,predominantly activated eosinophils and increased...
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How to Diagnose NOSE Polyps ? How to Cure Nose Polyps at Home ?

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To diagnose nose polps,  a fiberoptic rhinoscopic examination is essential to diagnose the Nose Polyps phenotype before initiating medical treatment. Anterior rhinoscopy only visualizes the anterior one- third of the nasal cavity and is inadequate to visualize the posterior nasal cavity and nasopharynx. Rhinoscopy is a simple, low-risk, cost-effective procedure that should be performed routinely in subjects with persistent upper airway problems. Just as office spirometry is a routine procedure to assist in the diagnosis of airflow obstruction, so too should rhinoscopy be used regularly for Nose Polyps. The primary objective outcome of phase III clinical trials of dupilumab and phase II clinical trials of other biologic agents is based on the Nose Polyps scores as determined by rhinoscopy. ’ Rhinoscopy is also important to identify other abnormalities of the nasal cavity, pharynx, and larynx. These abnormalities may include enlarged adenoids, often associated with sleep apnea in chi...
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Can Nasal Polyps Be Serious ? ( Must Read )

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Severe nasal polyposis can cause deformities of the nose and face. This phenomenon is called Woakes’ syndrome. The facial deformity in our patient was caused by pressure from nasal polyposis that filled the nasal cavity and paranasal sinuses. Using the midface degloving approach, we performed osteotomy of the nasal bone, shaved the .The facial deformity of Woakes’ syndrome involved the nasal and facial bones and nasal cartilaginous tissue. In severe cases, excessive prominence of the malar region and orbital hypertelorism have been reported . Patient had broadening of the nose and excessive prominence of the malar regions without orbital hypertelorism. We believe that inflammation associated with 30 years of chronic sinusitis caused enlargement of the nasal polyps, leading to the exertion of physical pressure on the neighbouring bones and cartilage.   Several reports discuss the cosmetic treatment of the nose after nasal polyp removal. Laff performed nasal plastic repair with osteo...
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