What are Glucocorticoids Nasal Spray Side Effects ?

New study shows that fibroblasts from patients with NPs and asthma who have a poor clinical response to Glucocorticoids Nasal  treatment, display a relative resistance to the anti-proliferative effects of glucocorticoids nasal,  compared to fibroblasts from control nasal mucosa. 

In addition, glucocorticoids nasal  failed to inhibit collagen expression in any fibroblast type. In contrast, GCs effectively down-regulated IL-6 and IL-8 production by nasal fibroblasts, though Nasal Polyps fibroblasts were less sensitive to dexamethasone than NM fibroblasts. 

Overall, our findings reinforce the concept that glucocorticoids nasal are less effective in reducing fibrosis and remodelling of the airways than in reducing inflammation. The study results also suggest that the impaired sensitivity of nasal polyp fibroblasts to the in vitro anti-proliferative and anti-inflammatory effects of glucocorticoids concurs in part with the poor clinical response that these nasal polyp patients show to glucocorticoid treatment.

Read more : Best way to get rid of Nasal Polyps naturally at Home

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